Manchester United and Aston Villa paid a heavy price for having men sent off on in the Premier League on Sunday with United losing a tight derby to Man City and Villa surrendering a lead in defeat by Tottenham Hotspur.
The Louis van Gaal era finally got lift off as Manchester United demolished Queens Park Rangers 4-0 on Sunday for their first win since the Dutchman took charge at Old Trafford.
Manchester United's Zlatan Ibrahimovic proved his hunger for silverware has not diminished with age as the Swede's double earned a 3-2 win over Southampton in an absorbing League Cup final at Wembley.
A plethora of high-profile attacking signings had expectant Manchester United fans dreaming of a return to the upper echelons of European football, but their failure to identify their defensive problems is threatening to derail those hopes.
Liverpool put their recent troubles behind them, showing touches of their best early-season vibrancy to overcame Arsenal 3-1 at a jubilant Anfield and leapfrog the Gunners into third place in the Premier League on Saturday.
Wayne Rooney ended his eight-game Premier League scoring drought with a 2-0 victory against a dogged Sunderland.
Unai Emery's side were heading for a demoralising defeat, three days after losing meekly to Sheffield United in the Premier League, but substitute Pepe's late intervention kept the Gunners top of Group F with a maximum nine points.
News of all that's transpired on and off the football field
News of all that's transpired on and off the football field
Rediff.com brings a preview of the main matches coming up this weekend in the English Premier League.
Manchester United opened up the Premier League title race with a convincing 2-0 home victory over leaders Chelsea on Sunday that leaves second-placed Tottenham Hotspur just four points behind.
Liverpool target Chelsea after midweek tinkering, while third-placed Manchester City, whose hopes of qualifying for the Champions League knockout stage were dealt a severe blow in a humiliating 2-1 home defeat by CSKA Moscow on Wednesday, travel south to face struggling Queens Park Rangers.
For Manchester United, the answer to a slump in form or a crisis of confidence comes in 50 pound notes. Millions of them.
A round-up of the 2018 World Cup qualifiers played on Thursday
If Manchester United are to claim a seventh successive Premier League victory and condemn leaders Chelsea to a first home league defeat of the season their manager Louis van Gaal must solve another complex injury puzzle.
Manchester City went 11 points clear with a record 14th consecutive Premier League win in an entertaining derby against Manchester United at Old Trafford.
Photos from the English Premier League matches played on Wednesday
A summary of Wednesday's matches in the UEFA Champions League.
News of all that's transpired on and off the football field